UPDATE ON GUIDELINES FOR THE TREATMENT OF COPD IN TAIWAN USING EVIDENCE AND GRADE SYSTEM-BASED RECOMMENDATIONS

Update on guidelines for the treatment of COPD in Taiwan using evidence and GRADE system-based recommendations

Chronic obstructive pulmonary disease (COPD) has significant contributions to morbidity and mortality world-wide.Early symptoms of COPD are not readily distinguishable, resulting in a low rate of diagnosis and intervention.Different guidelines and recommendatations for the diagnosis and treatment of COPD exist globally.The first edition of clinical

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Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19: Study Protocol for a Retrospective Observational Multicenter Study (SELECT)

BackgroundIn hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely.Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails.In critically ill patients, high-dose corticosteroids are often administered as salvag

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Enhanced control of Mycobacterium tuberculosis extrapulmonary dissemination in mice by an arabinomannan-protein conjugate vaccine.

Currently there are a dozen or so of new vaccine candidates in clinical trials for prevention of tuberculosis (TB) and each formulation attempts to elicit protection by enhancement of cell-mediated immunity (CMI).In contrast, most approved vaccines against other bacterial pathogens are believed to mediate protection by eliciting antibody responses.

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